Description

You will drive target validation and assay development through mechanistic experiments in cell and molecular biology.

Responsibilities

• Develop disease models to support SAR, mechanism of action, resistance, and biomarker selection.
• Implement cell-based assays to investigate tumor intrinsic biology and immune-based mechanisms.
• Design and conduct mechanistic experiments in cell biology, cellular biochemistry, and molecular biology.
• Maintain accurate written reports and present scientific results in an organized, timely manner.
• Collaborate across teams to support drug discovery efforts.

Required Skills

• Ph.D. in cell biology, immunology, molecular biology, or oncology with 0-2 years of post-doc or industry experience.
• M.S. degree with 3+ years of experience or B.S. degree with 5+ years of experience in biopharmaceutical industry.
• Extensive experience in multi-parameter flow cytometry for primary immune cell isolation and characterization.
• Hands-on experience with mammalian cell culture and molecular technologies including CRISPR/Cas9, lentiviral transduction, western blotting, and quantitative PCR.
• Proficiency in functional assays such as proliferation, apoptosis, and cell cycle analysis.
• Strong background in cancer research and molecular/cell biology.
• Proficiency in scientific data analysis using GraphPad Prism, FlowJo, and Microsoft Excel/PowerPoint.
• Proven record of rigorous science through publication history.

Preferred Skills

• Experience with IncuCyte, JESS, Flow based cell sorter, ELISA, and MSD in oncology-based drug discovery.

Key Skills

Education

Any Graduate